What's the Kennection? #162

At the end of the 2012 movie Skyfall, Ralph Fiennes became the latest actor to take on what role?

What musical key has no sharps or flats in its key signature?

Which of the two sex chromosomes in human cells is found in both males and females?

What 1983 NBC mini-series began with the arrival of fifty spaceships from the fourth planet orbiting Sirius?

What's the only pronoun that's always capitalized in English?

What's the "Kennection"?